Publications
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- Paper publication
- Efficacy and Safety of DA-8010, a Novel M3 Antagonist, in Patients With Overactive Bladder: A Randomized, Double-Blind Phase 2 Study. Int Neurourol J. 2022 Jun;26(2):119-128. doi: 10.5213/inj.2142382.191. Epub 2022 Jun 30. PMID: 35793990; PMCID: PMC9260321.Son HS, Oh CY, Choo MS, Kim HG, Kim JC, Lee KS, Shin DG, Cho SY, Jeong SJ, Seo JT, Yoon H, Moon HS, Kim JH.
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- Paper publication
- The effects of oral administration of the novel muscarinic receptor antagonist DA-8010 on overactive bladder in rat with bladder outlet obstruction. BMC Urol. 2020 Apr 17;20(1):41. doi: 10.1186/s12894-020-00611-8. PMID: 32303205; PMCID: PMC7164290. Choi JB, Jeon SH, Kwon EB, Bae WJ, Cho HJ, Ha US, Hong SH, Lee JY, Kim SW.
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- Paper publication
- Pharmacological characterization of DA-8010, a novel muscarinic receptor antagonist selective for urinary bladder over salivary gland. Eur J Pharmacol. 2019 Jan 15;843:240-250. doi: 10.1016/j.ejphar.2018.11.037. Epub 2018 Nov 28. PMID: 30502343. Lee MJ, Moon JH, Lee HK, Cho CH, Choi SH, Im WB.
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- Paper publication
- American Urological Association (AUA) - 111th Annual Meeting (May 6-10, 2016 - San Diego, California, USA).Drugs of today (Barcelona, Spain : 1998) vol. 52,5 (2016): 313-5. doi:10.1358/dot.2016.52.5.2505616. Croasdell, G.
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- Paper publication
- GPR119 activation by DA-1241 alleviates hepatic and systemic inflammation in MASH mice through inhibition of NFκB signaling. Biomed Pharmacother. 2023 Aug 30;166:115345. doi: 10.1016/j.biopha.2023.115345. PMID: 37657264Lee SH, Park H, Yang EK, Lee BR, Jung IH, Kim TH, Goo MJ, Chae Y, Kim MK.
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- Paper publication
- DA-1241, a Novel GPR119 Agonist, Improves Hyperglycaemia by Inhibiting Hepatic Gluconeogenesis and Enhancing Insulin Secretion in Diabetic Mice. Diabetes Metab J. 2022 Mar;46(2):337-348. doi: 10.4093/dmj.2021.0056. PMID: 35052026Kim Y, Lee SW, Wang H, Kim RH, Park HK, Lee H, Kang ES.
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- Paper publication
- A novel GPR119 agonist DA-1241 preserves pancreatic function via the suppression of ER stress and increased PDX1 expression. Biomed Pharmacother. 2021 Dec;144:112324. doi: 10.1016/j.biopha.2021.112324. Epub 2021 Oct 19. PMID: 34678732.Kim MK, Cheong YH, Lee SH, Kim TH, Jung IH, Chae Y, Lee JH, Yang EK, Park H, Yang JS, Hong KW.